How Can Treatment Change the Depression Brain?

  • Womenscorner Desk
  • December 6, 2020

Experts have found that balancing the quantity of cortisol and other chemicals within the brain can help reverse any shrinkage of the hippocampus and treat the memory problems it's going to cause. Correcting the body’s chemical levels also can help reduce symptoms of MDD. There are several common medications which will fight the negative effects of depression on the brain by helping to balance the chemicals within the brain. These include:

Selective serotonin uptake inhibitors (SSRIs): These drugs can help alleviate symptoms of MDD by changing the amount of a chemical called serotonin within the brain. Examples of SSRIs include fluoxetine (Prozac), paroxetine (Paxil), and citalopram (Celexa).

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Serotonin-norepinephrine reuptake inhibitors (SNRIs) and tricyclic antidepressants: When used together, these medications can relieve MDD symptoms by altering the amounts of serotonin and norepinephrine within the brain. These chemicals help boost mood and energy levels. samples of SNRIs include duloxetine (Cymbalta) and venlafaxine (Effexor XR). Imipramine (Tofranil), nortriptyline (Pamelor), and trimipramine (Surmontil) are samples of tricyclic antidepressants.

Norepinephrine-dopamine reuptake inhibitors (NDRIs): These medications aid people with MDD by increasing levels of the mood-boosting chemicals norepinephrine and dopamine within the brain. Bupropion (Wellbutrin) may be a sort of NDRI which will be used.

Monoamine oxidase inhibitors (MAOIs): These drugs help ease symptoms of MDD by increasing the quantity of norepinephrine, serotonin, and dopamine within the brain. They can also improve nerve cell communication.

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Atypical antidepressants: This group of medicines includes tranquilizers, mood stabilizers, and antipsychotics. These drugs can block nerve cell communication in order to relax the body. Besides medications, certain medical procedures also can affect the brain to assist ease symptoms of MDD. These include:

- Electroshock (ECT), which involves passing electrical currents through the brain to spice up communication between brain cells.

- Transcranial magnetic stimulation (TMS), which involves sending electrical pulses into the brain cells that regulate mood.

Researchers also believe that psychotherapy can alter brain structure and help relieve MDD symptoms. Specifically, psychotherapy appears to strengthen the prefrontal cortex. There are other ways to spice up brain health and help get over MDD without medical intervention. These include:

- Eating healthful foods and staying active, which stimulates brain cells and strengthens communication between brain cells.

- Sleeping well, which helps grow and repair brain cells.

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- Avoiding alcohol and illegal drugs, which may destroy brain cells.

Talk to your doctor about which treatments could also be best for you.

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